session 8 G&G case study

Session 8 Case StudyRead the case study and review the resources before completing the questions. Record your answers on a Word Document and include references in APA format for the resources you use to answer the assigned questions. This assignment is worth 15 points.Duchenne Muscular Dystrophy (DMD)Reviewing the case study presented in this week’s Learning Activity and the following resources, will aid in completing this assignment.Duchenne Muscular Dystrophy (DMD) ResourcesU.S. National Library of Medicine. (2017). Duchenne and Becker Muscular Dystrophy. MedlinePlus.https://medlineplus.gov/genetics/condition/duchenne-and-becker-muscular-dystrophy/U.S. National Library of Medicine. (2020). DMD Gene. MedlinePlus.https://medlineplus.gov/genetics/gene/dmd/Duchenne.com (n.d.) Understanding the science of Duchenne.https://www.duchenne.com/genetic-mutationsDuchenne UK. (2020). Gene therapy overview.https://www.duchenneuk.org/gene-therapy-overviewCarvalho, C. (2020). Gene editing restores dystrophin in pig model of Duchenne and patient cells, study reports. BioNews Services; Muscular Dystrophy.
Gene Editing Restores Dystrophin in Pig Model of Duchenne and Patient Cells, Study Reports
Muscular Dystrophy Association. (2019). The State of Gene-Targeted Therapies.https://www.mda.org/quest/article/state-gene-targeted-therapiesJohn Hopkins University’s Online Mendelian Inheritance in Man. (2019). Muscular Dystrophy, Duchenne Type; DMD, OMIM#310200.https://www.omim.org/entry/310200After familiarizing yourself with DMD, concisely answer the following questions:The DMD gene provides instructions for which protein, and what is the normal function of this protein? (3 pts)How do mutations in the DMD gene alter protein function and what are the resulting symptoms displayed in DMD patients? (4 pts)What types of genetic mutations are observed in the DMD gene and which is the most common? (Hint: see the Duchenne.com resource for the answer). (2 pts)In the future, how would gene replacement and gene-editing therapies be used to treat a patient with DMD? (3 pts)Knowing that the DMD gene is the longest gene in the human genome, would gene therapy or gene-editing therapy be a better approach to treat DMD? Explain. (3 pts)

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